| Total | 10 | 3 | (30%) | 5 | (50%) | 2 | (20%) |
| Heimspiele | 5 | 1 | (20%) | 3 | (60%) | 1 | (20%) |
| Auswärtsspiele | 5 | 2 | (40%) | 2 | (40%) | 1 | (20%) |
U | 2022-05-25 | Independiente Medellín |  | 1-1 |  | Guaireña FC | SP6 | ||
S | 2022-05-18 | Nueve de Octubre |  | 2-3 | | Guaireña FC | SP5 | ||
U | 2022-05-06 | Guaireña FC | | 1-1 |  | Internacional | SP4 | ||
S | 2022-04-28 | Guaireña FC | | 1-0 | | Nueve de Octubre | SP3 | ||
U | 2022-04-15 | Internacional | | 1-1 | | Guaireña FC | SP2 | ||
U | 2022-04-08 | Guaireña FC | | 3-3 | | Independiente Medellín | SP1 | ||
U | 2022-03-17 | Guaireña FC | | 0-0 |  | Nacional | 1F | ||
S | 2022-03-10 | Nacional | | 0-1 | | Guaireña FC | 1F | ||
N | 2021-04-09 | River Plate |  | 4-2 | | Guaireña FC | 1F | ||
N | 2021-03-18 | Guaireña FC | | 1-2 | | River Plate | 1F |
