| Datum | Anstoßzeit | Heimspiele | Auswärtsspiele | Fase | TV | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
S | 2021-07-18 | 23:15 | Olimpia |  | 1-3 |  | River Plate | SP1 | ||||
S | 2021-07-25 | 23:15 | Guaireña FC |  | 1-2 | | River Plate | SP2 | ||||
S | 2021-08-14 | 01:45 | River Plate | | 1-0 |  | Nacional | SP5 | ||||
S | 2021-09-12 | 00:00 | Sportivo Luqueño |  | 0-2 | | River Plate | SP8 | ||||
